{"id":6919,"date":"2022-08-31T13:46:33","date_gmt":"2022-08-31T04:46:33","guid":{"rendered":"https:\/\/www.wakakoukai.or.jp\/rihabili\/?p=6919"},"modified":"2022-08-31T13:52:12","modified_gmt":"2022-08-31T04:52:12","slug":"paper_220829","status":"publish","type":"post","link":"https:\/\/www.wakakoukai.or.jp\/rihabili\/paper_220829\/","title":{"rendered":"\u9662\u9577 \u9326\u898b\u4fca\u96c4\u306e\u82f1\u6587\u8ad6\u6587\u304c\u767a\u884c\u3055\u308c\u307e\u3057\u305f"},"content":{"rendered":"

\u9662\u9577 \u9326\u898b\u4fca\u96c4\u306e\u82f1\u6587\u8ad6\u6587\u304c\u767a\u884c\u3055\u308c\u307e\u3057\u305f\u3002<\/span><\/p>\r\n

\u307e\u305fGoogle Scholar\u306e\u5f15\u7528\u56de\u6570\u304c13,500\u56de\u3092\u8d85\u3048\u307e\u3057\u305f\u3002<\/span><\/p>\r\n

\uff08https:\/\/scholar.google.co.jp\/scholar?start=0&q=Toshio+Nishikimi&hl=ja&as_sdt=0,5<\/a>\uff09<\/p>\r\n

 <\/p>\r\n

\r\n
\r\n

 <\/p>\r\n

\u2015\u3000Circulation Research\u3000\u2015<\/span><\/h3>\r\n

\uff08American Heart Association\/<\/span>2022\u5e741\u6708\u767a\u884c\uff09<\/p>\r\n

 <\/p>\r\n

\r\n
\r\n

\"paper_p220829_JCirc-Res-cover\"<\/p>\r\n

\r\n

NRSF-GNAO1<\/i> Pathway Contributes to the Regulation of Cardiac Ca2+<\/sup> Homeostasis.<\/p>\r\n


\r\n Inazumi H, Kuwahara K, Nakagawa Y, Kuwabara Y, Numaga-Tomita T, Kashihara T, Nakada T, Kurebayashi N, Oya M, Nonaka M, Sugihara M, Kinoshita H, Moriuchi K, Yanagisawa H, Nishikimi T<\/span>, Motoki H, Yamada M, Morimoto S, Otsu K, Mortensen RM, Nakao K, Kimura T.<\/p>\r\n

 <\/p>\r\n

Circ Res. <\/a> 2022 Jan 21;130(2):234-248. doi: 10.1161\/CIRCRESAHA.121.318898<\/span>.<\/p>\r\n

 <\/p>\r\n

\uff08impact factor 17.367<\/span>\uff09<\/p>\r\n<\/div>\r\n

<\/div>\r\n<\/div>\r\n

 <\/p>\r\n

<\/p>\r\n

\u5fc3\u4e0d\u5168\u767a\u75c7\u6642\u306b\u306f\u3001\u80ce\u5150\u671f\u306e\u5fc3\u7b4b\u907a\u4f1d\u5b50\u30d7\u30ed\u30b0\u30e9\u30e0\u304c\u518d\u6d3b\u6027\u5316\u3057\u3001\u75c5\u7684\u5fc3\u7b4b\u30ea\u30e2\u30c7\u30ea\u30f3\u30b0\u3092\u52a0\u901f\u3055\u305b\u308b\u3002\u8ee2\u5199\u6291\u5236\u56e0\u5b50NRSF\uff08neuron restrictive silencer factor\uff09\u304c\u80ce\u5150\u5fc3\u7b4b\u907a\u4f1d\u5b50\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u6291\u5236\u3057\u3001\u305d\u308c\u306b\u3088\u3063\u3066\u5fc3\u7b4b\u306e\u5065\u5168\u6027\u304c\u7dad\u6301\u3055\u308c\u308b\u304c\u3001\u305d\u306e\u5206\u5b50\u6a5f\u69cb\u3068\u3057\u3066\u3001GNAO1\u304c\u30b3\u30fc\u30c9\u3059\u308b\u6291\u5236\u6027G\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3042\u308bG\u03b1o\u306e\u5fc3\u81d3\u3067\u306e\u767a\u73fe\u304cNRSF\u306b\u3088\u3063\u3066\u8ee2\u5199\u5236\u5fa1\u3055\u308c\u3001\u5fc3\u4e0d\u5168\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u306e\u5fc3\u5ba4\u3067\u5897\u52a0\u3057\u3001Ca2+<\/sup>\u30cf\u30f3\u30c9\u30ea\u30f3\u30b0\u306e\u969c\u5bb3\u3092\u5f15\u304d\u8d77\u3053\u3057\u3001\u5fc3\u6a5f\u80fd\u969c\u5bb3\u306b\u81f3\u308b\u3053\u3068\u3092\u793a\u3057\u305f\u3002<\/p>\r\n

 <\/p>\r\n<\/section>\r\n

 <\/p>\r\n

\u2015\u3000Biology\u3000\u2015<\/span><\/h3>\r\n

\uff08Molecular Diversity Preservation International<\/span>\/<\/span>2022\u5e742\u6708\u63b2\u8f09\uff09<\/p>\r\n

 <\/p>\r\n

\r\n

Cardiac Peptides-Current Physiology, Pathophysiology, Biochemistry, Molecular Biology, and Clinical Application.<\/p>\r\n


\r\n Nishikimi T, Kato J.<\/p>\r\n

 <\/p>\r\n

Biology (Basel). <\/a> 2022 Feb 18;11(2):330. doi: 10.3390\/biology11020330<\/span>.<\/p>\r\n

 <\/p>\r\n

\uff08impact factor\u00a0<\/span>5.168<\/span>\uff09<\/p>\r\n

 <\/p>\r\n

<\/p>\r\n

Biology\u8a8c\u306eSpecial Issue\u306e\u2019Cardiac Peptide\u2019\u306eGuest Editor\u3092\u5bae\u5d0e\u5927\u5b66\u533b\u5b66\u90e8\u306e\u52a0\u85e4\u4e08\u53f8\u6559\u6388\u3068\u884c\u3044\u3001Editorial\u3092\u57f7\u7b46\u3057\u305f<\/span>\u3002<\/p>\r\n

 <\/p>\r\n<\/section>\r\n

 <\/p>\r\n

\u2015\u3000Biology\u3000\u2015<\/span><\/h3>\r\n

\uff08Molecular Diversity Preservation International<\/span>\/<\/span>2022\u5e747\u6708\u63b2\u8f09\uff09<\/p>\r\n

 <\/p>\r\n

\r\n

B-Type Natriuretic Peptide (BNP) Revisited-Is BNP Still a Biomarker for Heart Failure in the Angiotensin Receptor\/Neprilysin Inhibitor Era?<\/p>\r\n


\r\n Nishikimi T, Nakagawa Y.<\/p>\r\n

 <\/p>\r\n

Biology (Basel). <\/a> 2022 Jul ;11(7):1034.<\/span><\/p>\r\n

https:\/\/www.mdpi.com\/2079-7737\/11\/7\/1034<\/p>\r\n

 <\/p>\r\n

\uff08impact factor\u00a0<\/span>5.168<\/span>\uff09<\/p>\r\n

 <\/p>\r\n

<\/p>\r\n

\u6d3b\u6027\u578bBNP-32\u3001\u4f4e\u6d3b\u6027\u578bproBNP-108\u3001\u4e0d\u6d3b\u6027\u578bN\u672b\u7aefproBNP-76\u306f\u3059\u3079\u3066\u8840\u4e2d\u3092\u5faa\u74b0\u3057\u3066\u3044\u308b\u3002\u8840\u4e2d\u306e\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc\u3067\u3042\u308b\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u306f\u3001BNP\u306b\u5bfe\u3059\u308b\u57fa\u8cea\u7279\u7570\u6027\u304cANP\u3088\u308a\u3082\u4f4e\u304f\u3001proBNP\u3068N-terminal proBNP\u306f\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u306b\u3088\u3063\u3066\u5206\u89e3\u3055\u308c\u306a\u3044\u3002\u73fe\u72b6\u306eBNP\u6e2c\u5b9a\u7cfb\u306fmature BNP\u3068proBNP\u306e\u4e21\u65b9\u306b\u53cd\u5fdc\u3059\u308b\u306e\u3067\u3001\u8840\u6f3f\u4e2d\u306eBNP\u6e2c\u5b9a\u5024\u306fmature BNP + proBNP\u3067\u3042\u308b\u3002ARNI\u6295\u4e0e\u306b\u3088\u308amature BNP\u304c\u5897\u52a0\u3059\u308b\u305f\u3081\u3001\u8840\u6f3fBNP\u6e2c\u5b9a\u5024\u306fmature BNP\u306e\u5897\u52a0\u5206\u3060\u3051ARNI\u6295\u4e0e\u306b\u3088\u308a\u521d\u671f\u306b\u5897\u52a0\u3059\u308b\u3002\u305d\u306e\u5f8c\u3001ARNI\u6295\u4e0e\u306b\u3088\u308a\u5fc3\u7b4b\u306e\u58c1\u5fdc\u529b\u304c\u4f4e\u4e0b\u3057\u3001\u305d\u306e\u7d50\u679cBNP\u7523\u751f\u304c\u6e1b\u5c11\u3057\u3001\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u306b\u3088\u308b\u5206\u89e3\u306e\u963b\u5bb3\u306b\u3088\u308bmature BNP\u306e\u5897\u52a0\u3092\u76f8\u6bba\u3057\u3001\u8840\u6f3fBNP\u6fc3\u5ea6\u304c\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u306b\u306a\u308b\u3002ARNI\u6642\u4ee3\u306b\u304a\u3044\u3066\u3082\u3001BNP\u306f\u5fc3\u4e0d\u5168\u306e\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3068\u3057\u3066\u6709\u7528\u3067\u3042\u308b\u304c\u3001ARNI\u6295\u4e0e\u4e2d\u306e\u65e9\u671f\u306e\u8efd\u5ea6\u4e0a\u6607\u306b\u306f\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3042\u308b\u3001\u3053\u3068\u3092\u793a\u3057\u305f\u3002<\/span><\/p>\r\n

 <\/p>\r\n<\/section>\r\n

\u2015\u3000Biology\u3000\u2015<\/span><\/h3>\r\n

\uff08Molecular Diversity Preservation International<\/span>\/<\/span>2022\u5e746\u6708\u63b2\u8f09\uff09<\/p>\r\n

 <\/p>\r\n

\r\n

CNP,\u00a0<\/span>the Third Natriuretic Peptide: Its Biology and Significance to the Cardiovascular System?<\/p>\r\n


\r\n Nakagawa Y, Nishikimi T.<\/p>\r\n

 <\/p>\r\n

Biology (Basel). <\/a> 2022 Jun ;11(7):986.<\/span><\/p>\r\n

https:\/\/www.mdpi.com\/2079-7737\/11\/7\/986<\/p>\r\n

 <\/p>\r\n

\uff08impact factor\u00a0<\/span>5.168<\/span>\uff09<\/p>\r\n

 <\/p>\r\n

<\/p>\r\n

CNP \u306f\u30013 \u756a\u76ee\u306b\u5358\u96e2\u3055\u308c\u305f\u30ca\u30c8\u30ea\u30a6\u30e0\u5229\u5c3f\u30da\u30d7\u30c1\u30c9\u3067\u3042\u308a\u3001\u4e2d\u67a2\u795e\u7d4c\u7cfb\u3001\u9aa8\u8edf\u9aa8\u7cfb\u3001\u8840\u7ba1\u7cfb\u306b\u5e83\u304f\u767a\u73fe\u3057\u3066\u3044\u308b\u3002CNP \u304c\u4e3b\u306b\u6a19\u7684\u3068\u3059\u308b\u53d7\u5bb9\u4f53\u306f GC-B \u3067\u3042\u308a\u3001\u4ed6\u306e 2 \u7a2e\u985e\u306e\u30ca\u30c8\u30ea\u30a6\u30e0\u5229\u5c3f\u30da\u30d7\u30c1\u30c9\u3001ANP \u304a\u3088\u3073 BNP \u304c\u6a19\u7684\u3068\u3059\u308b\u53d7\u5bb9\u4f53\u3067\u3042\u308b GC-A \u3068\u306f\u7570\u306a\u308b\u3002\u5fc3\u8840\u7ba1\u7cfb\u3067\u306fCNP\u306f\u5fc3\u81d3\u306e\u30ea\u30e2\u30c7\u30ea\u30f3\u30b0\u3092\u6291\u5236\u3057\u5fc3\u7b4b\u6897\u585e\u306e\u4e88\u9632\u306b\u5bc4\u4e0e\u3059\u308b\u3053\u3068\u3001\u8840\u7ba1\u6a5f\u80fd\u3068\u8840\u5727\u306e\u8abf\u7bc0\u306b\u5bc4\u4e0e\u3059\u308b\u3053\u3068\u3001\u8840\u7ba1\u306e\u30ea\u30e2\u30c7\u30ea\u30f3\u30b0\u3068\u8840\u7ba1\u65b0\u751f\u3092\u5236\u5fa1\u3059\u308b\u3053\u3068\u3001\u5fc3\u81d3\u306e\u9593\u8cea\u6027\u7dda\u7dad\u5316\u304a\u3088\u3073\u7dda\u7dad\u5316\u95a2\u9023\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u306a\u3069\u304b\u3089\u3001CNP\u306e\u5fc3\u8840\u7ba1\u7cfb\u75be\u60a3\u6cbb\u7642\u85ac\u3068\u3057\u3066\u306e\u81e8\u5e8a\u5fdc\u7528\u304c\u671f\u5f85\u3055\u308c\u308b\u3053\u3068\u3092\u793a\u3057\u305f\u3002<\/span><\/p>\r\n

 <\/p>\r\n<\/section>\r\n<\/div>\r\n<\/div>\r\n

\u9326\u898b\u9662\u9577\u306f\u3001\u5fc3\u81d3\u8840\u7ba1\u7cfb\u306e\u7814\u7a76\u309230\u5e74\u4ee5\u4e0a\u7d9a\u3051\u3066\u304a\u308a<\/span>\u3001\u82f1\u6587\u8ad6\u6587\u3082\u591a\u6570\u767a\u8868\u3057\u3066\u3044\u307e\u3059\u3002<\/p>","protected":false},"excerpt":{"rendered":"

\u9662\u9577 \u9326\u898b\u4fca\u96c4\u306e\u82f1\u6587\u8ad6\u6587\u304c\u767a\u884c\u3055\u308c\u307e\u3057\u305f\u3002 \u307e\u305fGoogle Scholar\u306e\u5f15\u7528\u56de\u6570\u304c13,500\u56de\u3092\u8d85\u3048\u307e\u3057\u305f\u3002 \uff08https:\/\/scholar.google.co.jp\/scholar?start=0&q […]<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/www.wakakoukai.or.jp\/rihabili\/wp-json\/wp\/v2\/posts\/6919"}],"collection":[{"href":"https:\/\/www.wakakoukai.or.jp\/rihabili\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wakakoukai.or.jp\/rihabili\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wakakoukai.or.jp\/rihabili\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wakakoukai.or.jp\/rihabili\/wp-json\/wp\/v2\/comments?post=6919"}],"version-history":[{"count":13,"href":"https:\/\/www.wakakoukai.or.jp\/rihabili\/wp-json\/wp\/v2\/posts\/6919\/revisions"}],"predecessor-version":[{"id":6933,"href":"https:\/\/www.wakakoukai.or.jp\/rihabili\/wp-json\/wp\/v2\/posts\/6919\/revisions\/6933"}],"wp:attachment":[{"href":"https:\/\/www.wakakoukai.or.jp\/rihabili\/wp-json\/wp\/v2\/media?parent=6919"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wakakoukai.or.jp\/rihabili\/wp-json\/wp\/v2\/categories?post=6919"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wakakoukai.or.jp\/rihabili\/wp-json\/wp\/v2\/tags?post=6919"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}